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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
Authors:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Favorite  |  View/Download：35/0  |  Submit date：2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease 期刊论文
BIOFABRICATION, 2024, 卷号: 16, 期号: 1, 页码: 13
Authors:  Du, Yu;  de Jong, Iris E. M.;  Gupta, Kapish;  Waisbourd-Zinman, Orit;  Har-Zahav, Adi;  Soroka, Carol J.;  Boyer, James L.;  Llewellyn, Jessica;  Liu, Chengyang;  Naji, Ali;  Polacheck, William J.;  Wells, Rebecca G.
Favorite  |  View/Download：372/0  |  Submit date：2023/11/28
microfluidic device  cholangiopathy  tissue engineering  organ-on-a-chip  primary sclerosing cholangitis  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
Authors:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  Favorite  |  View/Download：79/5  |  Submit date：2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
A fetal wound healing program after intrauterine bile duct injury may contribute to biliary atresia 期刊论文
JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 6, 页码: 13
Authors:  de Jong, Iris EM;  Hunt, Mallory L;  Chen, Dongning;  Du Y(杜宇);  Llewellyn, Jessica;  Gupta, Kapish;  Li, David;  Erxleben, Dorothea;  Rivas, Felipe;  Hall, Adam R;  Furth, Emma E;  Naji, Ali;  Liu, Chengyang;  Dhand, Abhishek;  Burdick, Jason A;  Davey, Marcus G;  Flake, Alan W;  Porte, Robert J;  Russo, Pierre A;  Gaynor, J William;  Wells, Rebecca G
Adobe PDF(6669Kb)  |  Favorite  |  View/Download：120/12  |  Submit date：2024/01/22
biliary atresia  hyaluronic acid  peribiliary glands  cholangiocyte  cholangiopathy  
A Biomimetic Liver Regeneration Chip for Studying Synergistic Effects of Mechanical Stretch and Shear Stress 会议论文
第二十次中国暨国际生物物理大会, 长沙, 2023年7月19日-23日
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Du Y(杜宇);  Long M(龙勉)
Favorite  |  View/Download：2/0  |  Submit date：2024/06/04
Coupling of Shear Stress and Stretch in a Biomimetic Liver Regeneration Chip (LRC) 会议论文
2023年中国生物医学工程大会暨创新医疗峰会, 苏州, 2023年5月18日-21日
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Du Y(杜宇);  Long M(龙勉)
Favorite  |  View/Download：0/0  |  Submit date：2024/06/04
A Liver Regeneration Chip for Orchestrating Mechanical Stretch and Shear Stress 会议论文
2023北京生物力学博士论坛, 北京, 45234
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Du Y(杜宇);  Long M(龙勉)
Favorite  |  View/Download：0/0  |  Submit date：2024/06/04
Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282
Authors:  Li W(李旺);  Li PW(李培文);  Li N(李宁);  Du Y(杜宇);  Lv SQ(吕守芹);  Elad, David;  Long M(龙勉)
Adobe PDF(2812Kb)  |  Favorite  |  View/Download：223/109  |  Submit date：2022/10/25
hepatocytes  liver fibrosis  matrix stiffness  shear flow  three-dimensional liver sinusoidal model  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
View  |  Adobe PDF(1593Kb)  |  Favorite  |  View/Download：592/284  |  Submit date：2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
组织硬度对肝血窦内皮细胞筛孔演化的调控及其力学信号转导机制 会议论文
第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议会议, 中国陕西西安, 2018年8月17日至21日
Authors:  李珮文;  李宁;  杜宇;  龙勉
View  |  Adobe PDF(158Kb)  |  Favorite  |  View/Download：224/75  |  Submit date：2019/11/21
肝血窦内皮细胞  毛细血管  基底硬度