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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
Authors:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Favorite  |  View/Download：34/0  |  Submit date：2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
Authors:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  Favorite  |  View/Download：79/5  |  Submit date：2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
力学拉伸调控肝血窦内皮细胞旁分泌及信号转导机制 学位论文
博士论文，北京: 中国科学院大学, 2023
Authors:  武亿
Adobe PDF(31496Kb)  |  Favorite  |  View/Download：153/3  |  Submit date：2023/07/06
肝再生  力学拉伸  肝血窦内皮细胞  旁分泌  信号转导  
Biomechanics in liver regeneration after partial hepatectomy 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651
Authors:  Wu Y(武亿);  Li N(李宁);  Shu XY(舒芯钰);  Li W(李旺);  Zhang XY(张晓宇);  Lv DY(吕东媛);  Long M(龙勉)
Adobe PDF(2065Kb)  |  Favorite  |  View/Download：87/6  |  Submit date：2023/07/17
liver regeneration  partial hepatectomy  hemodynamics  mechanical loading  mechanotransduction  
Receptor-Ligand Binding: Effect of Mechanical Factors 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 9062
Authors:  Du, Ruotian;  Li L(李龙);  Ji, Jing;  Fan, Yubo
Adobe PDF(2331Kb)  |  Favorite  |  View/Download：43/3  |  Submit date：2023/06/15
receptor-ligand binding  tension  shear stress  stretch  compression  substrate stiffness  biomechanics  mechanotransduction  
Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20
Authors:  Li W(李旺);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang ZL(张子良);  Sun SJ(孙树津);  Li N(李宁);  Long M(龙勉)
Adobe PDF(1498Kb)  |  Favorite  |  View/Download：134/3  |  Submit date：2023/03/20
microgravity  liver metabolism  mechanosensing  cytoskeleton  nuclear deformation  phase separation  
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis 期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
Authors:  Wang, Jin;  Xie, Si-an;  Li N(李宁);  Zhang, Tao;  Yao, Weijuan;  Zhao, Hucheng;  Pang, Wei;  Han, Lili;  Liu, Jiayu;  Zhou, Jing
Adobe PDF(21819Kb)  |  Favorite  |  View/Download：322/37  |  Submit date：2022/06/10
Matrix stiffness  Inflammation  DDR1  DNMT1  Mechanotransduction  
真核细胞运动接触抑制行为的力学-化学耦合模拟 期刊论文
中国科学:物理学 力学 天文学, 2022, 卷号: 52, 期号: 12, 页码: 145-155
Authors:  陈亚君;  周吕文;  冯世亮;  吕守芹;  龙勉
Adobe PDF(2973Kb)  |  Favorite  |  View/Download：169/60  |  Submit date：2023/02/09
细胞骨架重组  力敏感信号通路  格子玻尔兹曼法  
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
Authors:  Li N(李宁);  Zhang XY(张晓宇);  Zhou J(周瑾);  Li W(李旺);  Shu XY(舒芯钰);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(2553Kb)  |  Favorite  |  View/Download：369/109  |  Submit date：2022/10/23
Liver tissue stiffness  Shear stress  Hydrostatic pressure  Hepatocytes  Hepatocellular carcinoma  Liver sinusoidal endothelial cells  Hepatic stellate cells  Mechanotransduction pathways  Mechanomedicine  Drug design and delivery  
细胞力学2021年度研究进展 期刊论文
医用生物力学, 2022, 卷号: 37, 期号: 04, 页码: 584-590
Authors:  李宁;  龙勉
Adobe PDF(490Kb)  |  Favorite  |  View/Download：302/94  |  Submit date：2022/10/17
细胞力学  力学-生物学耦合  力学微环境